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Rhode Island News Study shows booster shot after 6 to 12 months likely to provide best protection from COVID-19, Pfizer says Credit to ABC News/Mark Osborne and Eric M. Strauss July 8, 2021 5:17 pm Pfizer and BioNTech have released initial data from a study on booster shots for their COVID-19 vaccine, saying a third dose delivered about six months after the second shot has shown neutralization titers are five to 10 times higher than after two primary doses. The companies said they expect to publish “more definitive data” soon and submit the Food and Drug Administration “in the coming weeks.” Pfizer said real-world evidence from Israel showed a decrease in efficacy about six months after people were fully vaccinated.

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