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Kombucha Tea-associated microbes remodel host metabolic pathways to suppress lipid accumulation

Kombucha Tea-associated microbes remodel host metabolic pathways to suppress lipid accumulation
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Modeling the interaction between the intestine and liver in a multi-organ microphysiological system for studying metabolic-dysfunction associated steatotic liver disease

Modeling the interaction between the intestine and liver in a multi-organ microphysiological system for studying metabolic-dysfunction associated steatotic liver disease
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Canagliflozin reduces atherosclerosis and modulates inflammatory, oxidative pathways in mice

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This study was aimed at investigating the effect of canagliflozin (Cana) on atherosclerosis and further exploring its potential mechanism. ApoE−/− mice were fed a Western diet (WD) and randomly divided into a WD group and WD+Cana group.

Compuscript ltdSoil redCardiovascular innovationsOxidative stress

A high-protein diet and elevation in the amino acid leucine may contribute to buildup of plaque in arteries

Researchers conducted clinical studies on murine animals and humans to evaluate the impact of high protein intake on the amino acid-mammalian target of the rapamycin complex 1 autophagy signaling pathway.

Crevis shutterstockSoil redNature metabolismAmino acidCardiovascular diseaseN vivoMass spectrometryIgnaling pathway

Multispecies transcriptomics identifies SIKE as a MAPK repressor that prevents NASH progression

Multispecies transcriptomics identifies SIKE as a MAPK repressor that prevents NASH progression
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