Cancer biologist Yibin Kang has been investigating the gene <i>MTDH</i>, which enables cancer in two ways. He has found a way to disable the gene in both mice and in human tissue, with a targeted experimental therapy.
In mice and in human tissue, a new compound discovered at Princeton disables a key gene that’s implicated in breast, prostate, liver, lung, colon and other cancers.
Imagine you could cure cancer by targeting one tiny gene. Imagine that same gene occurred in every major cancer, including breast, prostate, lung, liver
Rabinowitz leads research into cancer metabolism as director of new Ludwig Princeton Branch
Wendy Plump, Department of Chemistry
April 13, 2021 9:54 a.m.
Professors Yibin Kang and Joshua Rabinowitz, two of the three founding members of the new Ludwig Princeton Branch, are pictured in front of a fluorescent background image created by the Kang Lab.
Image courtesy of Matilda Luk, Office of Communications and Rumela Charkrabarti
Joshua Rabinowitz looks back over a string of collaborations that have led to today s announcement of a new branch of the Ludwig Institute for Cancer Research at Princeton University.
He cites Craig Thompson, then head of Penn Medicine’s Abramson Cancer Center and now president of Memorial Sloan Kettering, who brought nearly a dozen researchers to visit Rabinowitz’s lab in 2008, when Rabinowitz was a little-known junior faculty member; the renowned cancer physician and scientist Chi Van Dang, who would become the scientific director at