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Extended Follow-up of ALPINE Randomized Phase 3 Study Confirms Sustained Superior Progression-free Survival of Zanubrutinib Versus Ibrutinib for Treatment of Relapsed/Refractory Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma (R/R CLL/SLL)

Jennifer R. Brown, MD, PhD, presents data from the extended follow-up of the ALPINE study investigating zanubrutinib in relapsed/refractory chronic lymphocytic leukemia and small lymphocytic lymphoma.

San diegoUnited statesJenniferr brownExtended follow upZanubrutinib versus ibrutinibRefractory chronic lymphocytic leukemiaSmall lymphocytic lymphomaPartnership withAlpine studyChronic lymphocytic leukemiaBtk inhibitorCll treatmentAlpine trialAlpine study dataAlpine study resultsAlpine extended follow up

Venetoclax Is Associated With Durable ORRs in Real-World Population of BTK Inhibitor–Exposed CLL/SLL

Venetoclax-based therapy generated durable responses both overall and in the second or third line following covalent BTK inhibitor discontinuation in real-world patients with chronic lymphocytic leukemia or small lymphocytic lymphoma.

North carolinaUnited statesNilanjan ghoshDepartment of hematologic oncologyHematologic oncologyBlood disordersAtrium health levine cancer instituteReal world evidenceVenetoclax based therapyPatients with chronic lymphocytic leukemiaSmall lymphocytic lymphoma

Pirtobrutinib Demonstrates Durable Efficacy in Covalent BTK Inhibitor–Pretreated CLL/SLL

Pirtobrutinib continued to showcase clinically meaningful efficacy in heavily pretreated patients with chronic lymphocytic leukemia or small lymphocytic lymphoma who had prior exposure to a covalent BTK inhibitor.

Pirtobrutinib jaypircaJennifera woyachDivision of hematologyLeukemia research programOhio state universityOhio state university comprehensive cancer centerPatients with chronic lymphocytic leukemiaSmall lymphocytic lymphomaBruin studyThe ohio state university comprehensive cancer center

Small Lymphocytic Lymphoma Pipeline, FDA Approvals, Clinical Trials Developments, Companies 2023 | Loxo Oncology, Chia Tai Tianqing Pharmaceutical Group, Iovance Biotherapeutics, and others

DelveInsight s, Small Lymphocytic Lymphoma Pipeline Insight 2023 report provides comprehensive insights about 80+ companies and 80+ pipeline drugs in Small Lymphocytic Lymphoma pipeline landscape. It.

United kingdomUnited statesLas vegasJiangsu mingsightIovance biotherapeuticsYash bhardwajAscentage pharmaLoxo oncology incSmall lymphocytic lymphoma companiesDelveinsight business researchChia tai tianqing pharmaceutical groupRoute of administrationMingsight pharmaceuticalsChia tai tianqing pharmaceutical group drugCompany name drugLymphocytic lymphoma pipeline insight

FDA Approves Pirtobrutinib for Previously Treated CLL/SLL

The approval is the second this year for the reversible, highly selective kinase inhibitor following a January approval in mantle cell lymphoma.

United statesEli lillyWilliamg wierdaUniversity of texas md anderson cancer centerDrug administrationCancer centerMantle cell lymphomaSmall lymphocytic lymphomaMall lymphocytic lymphoma sllMalignant lymphomaChronic lymphocytic leukemia lymphoid cll leukaemiaAlignant neoplasiaAlignant neoplasmUs food and drug administration

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