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H. Lee Moffitt Cancer Center & Research Institute TAMPA, Fla. Melanocytic nevi, or moles, are nonmalignant growths that arise from pigment producing cells of the skin. They are mostly found in sun-exposed areas; however, they also can be found in sun-protected areas, such as the palms, soles of feet and nail beds, where they are known as acral nevi. While the mutation profile of nevi in sun-exposed areas is well understood, less is known about the genes that are commonly mutated in acral nevi. And while a subset of melanoma of sun-exposed skin arises in nevi, the link between nevi and melanoma in acral skin is poorly understood. In a new study published in JAMA Dermatology, Moffitt Cancer Center researchers report on the mutation profile of acral nevi and describe differences between acral nevi and acral melanoma.

United statesJane messinaKeiran smalleyMoffitt donalda adamSkin cancer centerDepartment of cutaneous oncologyMoffitt cancer centerMortality rateSkin cancerஒன்றுபட்டது மாநிலங்களில்ஜேன் மெசினாகேரான் ஸ்மல்லிதோல் புற்றுநோய் மையம்மாஃபிட் புற்றுநோய் மையம்