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Transcripts For CSPAN2 Book TV Encore Booknotes 20130302

Scientists and explores his private life. Cspan denis brian, author of einstein a life, why did you devote a chapter to einsteins brain . Guest it was such shocking news when i found out that somebody had got his brain. And it was exactly what he didnt want to happen. He told everyone that he didnt want any physical part of him to remain. He didnt want any memorials made to him. He didnt want his home made into a memorial. So that when i heard somebody had his brain, and they were slicing it up to find out clues to his genius, i thought this is perhaps the worst thing that could have ever happened to this man. Cspan where is his brain . Guest several scientists have it. The man who took the brain has most of it. And a japanese scientist has some, and theres a doctor in philadelphia has other parts of it. And the conclusion is that its absolutely ridiculous to search for genius in the brain, and that all they can say about it is its remarkably healthy for a man his age. Cspan who took t

MyJournals org - Science - [ASAP] Direct Measurement of Microplastics by Carbon Detection via Single Particle ICP-TOFMS in Complex Aqueous Suspensions (Environmental Science & Technology)

MyJournals org - Science - [ASAP] A Tale of Two Foulants: The Coupling of Organic Fouling and Mineral Scaling in Membrane Desalination (Environmental Science & Technology)

Ben Roy Mottelson Dies at 95; Shed Light on the Shape of Atoms

Cooperative Chikungunya Virus Membrane Fusion and Its Substoichiometri by Jelle S Blijleven, Ellen M Bouma et al

Chikungunya virus (CHIKV) presents a major burden on healthcare systems worldwide, but specific treatment remains unavailable. Attachment and fusion of CHIKV to the host cell membrane is mediated by the E1/E2 protein spikes. We used an in vitro single-particle fusion assay to study the effect of the potent, neutralizing antibody CHK-152 on CHIKV binding and fusion. We find that CHK-152 shields the virions, inhibiting interaction with the target membrane and inhibiting fusion. The analysis of the ratio of bound antibodies to epitopes implied that CHIKV fusion is a highly cooperative process. Further, dissociation of the antibody at lower pH results in a finely balanced kinetic competition between inhibition and fusion, suggesting a window of opportunity for the spike proteins to act and mediate fusion, even in the presence of the antibody.

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