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Many melanoma patients could avoid the risk for toxicity from combination therapies, study suggests

Data from a national clinical trial shows that a striking 89% of patients with desmoplastic melanoma responded to immunotherapy (pembrolizumab) alone, suggesting that many patients could avoid the risk for toxicity from combination therapies and achieve cancer control with this approach to treatment.

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High Response Rate to Pembrolizumab in Unresectable Desmoplastic Melanoma Trial

High Response Rate to Pembrolizumab in Unresectable Desmoplastic Melanoma Trial
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Immunotherapy Shows Exceptional Response Rates in Melanoma Patients

Immunotherapy Shows Exceptional Response Rates in Melanoma Patients
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SWOG S1512 trial sees high response rate to p

Close to 90 percent of patients with unresectable (inoperable) desmoplastic melanoma, a rare form of skin cancer, saw their cancer improve after treatment with the immunotherapy drug pembrolizumab in a recent clinical trial. These results from the S1512 trial are being delivered in an oral presentation at the clinical trials plenary session of the 2023 annual meeting of the American Association for Cancer Research (AACR) in Orlando, Florida, on April 16th.

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Reversing resistance to PD-1 inhibitors with combination immunotherapy in patients with advanced melanoma

Reversing resistance to PD-1 inhibitors with combination immunotherapy in patients with advanced melanoma
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