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ADCs, CDK4/6 Inhibitors, and SERDs Broaden HR+ and Triple-Negative Breast Cancer Treatment Paradigms

Novel data with trastuzumab deruxtecan, sacituzumab govitecan, and ribociclib have demonstrated an influx of overall survival advantages compared with standard-of-care regimens across breast cancer patient subsets, including HER2-positive, hormone receptor–positive, and triple-negative disease.

United statesHeather mcarthurJoyce oshaughnessyBreast cancer programUt southwestern medical centerDepartment of internal medicineClinical breast cancer researchBaylor charlesa sammons cancer centerDivision of hematologyKomen distinguished chairInternal medicineMedical centerShanu modiJoyceo shaughnessyTexas oncology baylor charlesCancer center

These Major Breakthroughs of 2022 Will Affect Health for Years to Come

Here are the biggest inventions and advances of 2022, from scientists, doctors, and health care advocates who reached incredible milestones.

United statesSan antonioJuliette cubanskiJonathan morrisMatt harrison cloughMeryl davids landauDaiichi sankyoPeter hotezKaiser family foundationGuttmacher instituteSupreme courtTexas children hospital centerUniversity of pittsburghVaccine developmentMemorial sloan kettering cancer centerAnatomic modeling unit

Year in Review: Breast Cancer

Practice-changing therapy for HER2-low breast cancer, potential for some women to skip surgery

United statesFrance generalIsrael generalDana farber cancer instituteUniversity of pennsylvaniaComunidad autonoma de catalunaAngela demicheleHeathera parsonsJane lowe meiselAnnelie johanssonHenry kuererNancy davidsonMeritxell bellet ezquerraKarolinska instituteAmerican society of clinical oncologyMd anderson cancer center

Cancer Breakthroughs Session at ASTRO2022 Unveils Key Findings from ASCO, AAPM

During a highly-anticipated “Cancer Breakthroughs” session at ASTRO2022, incoming ASTRO President Jeff Michalski, MD, MBA, FASTRO, moderated the presentation of significant findings from representatives of ASCO and AAPM.

United statesDana farber cancer instituteUniversity of chicagoSan antonioNosayaba oxazuwa petersMartha matuszakTakayuki yoshinoAndrea cercekKentonj johnsonJeff michalskiJustinm barnesAmerican society of clinical oncologyBlood disorders centerChildren oncology groupWashington university school of medicineUniversity of michigan

AstraZeneca and Daiichi Sankyo get FDA approval for breast cancer drug

AstraZeneca and Daiichi Sankyo get FDA approval for breast cancer drug
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Daiichi sankyo enhertuNational cancer instituteDrug administrationMemorial sloan kettering cancer centerDaiichi sankyoShanu modi