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Thick plumes of smoke billowed overhead from the building in Radcliffe, Greater Manchester, with witnesses reporting them visible from miles away as crews desperately tried to bring the fire under control

Greater manchesterUnited kingdom generalUnited kingdomShannon etteyBuilding chemical research ltdMount sionGreater manchester fireRescue serviceManchester eveningCommand support unitTechnical response unitHose laying lorryTurntable ladderManchester centralMount sion road