E-Mail
Humoral and cellular adaptive immunity are two immune mechanisms that act against pathogens. Humoral immunity is mediated by antibodies, while cellular immunity does not involve antibodies and is, instead, facilitated by T cells. Studying how these immune mechanisms mediate SARS-CoV-2 infections could be beneficial in controlling the progression of the disease. However, their roles in viral control or disease pathogenesis is not fully understood and only a few studies have thoroughly monitored COVID-19 patients longitudinally, especially during the acute phase of infection.
To fill this knowledge gap, the team of researchers at Duke-NUS investigated the changes in virological and immunological parameters in 12 patients with symptomatic acute SARS-CoV-2 infection from onset of the disease to recovery or death.
1 in 3 adults anxious, depressed due to COVID-19: Study ANI | Updated: Jan 28, 2021 15:58 IST
Washington [US], January 28 (ANI): A new study has discovered that one in every three adults, especially younger adults, women, and those of lower socioeconomic status experience psychological distress related to COVID-19.
Researchers at Duke-NUS Medical School, Singapore reported in the journal PLOS ONE that COVID-19 continues to pose serious threats to public health across the globe, and interventions such as lockdowns, quarantine, and social distancing are having an adverse impact on the mental well-being of populations.
The pandemic has escalated the burden of psychological distress, including anxiety, depression, post-traumatic stress, and insomnia. However, the factors associated with increased susceptibility to psychological distress among adults in the general population during COVID-19 are not yet well known.
Researchers design armored immune cells to attack recurring cancer in liver transplant patients
Duke-NUS Medical School researchers, together with collaborators in Singapore, have designed armored immune cells that can attack recurring cancer in liver transplant patients, while temporarily evading immunosuppressant drugs patients take to avoid organ rejection. The findings were published in the journal
Hepatology.
Hepatocellular carcinoma is the most common type of primary liver cancer and the sixth most common cancer worldwide. It often develops in people with chronic liver disease following hepatitis B infection.
A common treatment for hepatocellular carcinoma is to completely remove the liver and replace it with a healthy one from a donor. However, hepatitis B-related hepatocellular carcinoma can recur in some patients following transplantation. To kill the cancer, doctors can inject immune cells, called T cells, which are specially designed to target hepatitis B material fou
Singapore designs armoured anti-cancer T cells against immunosuppressants 19 January 2021 | News New ‘armoured’ T cells attack cancer without being suppressed by drugs given to transplant patients to avoid organ rejection.
Photo Credit: Freepik
Duke-NUS Medical School researchers, together with collaborators in Singapore, have designed armoured immune cells that can attack recurring cancer in liver transplant patients, while temporarily evading immunosuppressant drugs patients take to avoid organ rejection. The findings were published in the journal
Hepatology.
Hepatocellular carcinoma is the most common type of primary liver cancer and the sixth most common cancer worldwide. It often develops in people with chronic liver disease following hepatitis B infection.