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Using AI to find optimal combination of available therapies against SARS-CoV-2 A team of researchers from the National University of Singapore (NUS) has utilized a ground-breaking artificial intelligence (AI) platform to derive an optimal combination of available therapies against SARS-CoV-2, the cause of COVID-19. Their results showed that the optimal drug therapy was a combination of the drugs remdesivir, ritonavir, and lopinavir at specific doses. Remdesivir is a broad antiviral medication that was recently approved by the United States Food and Drug Administration as a treatment for COVID-19. The team showed that a combination of remdesivir with ritonavir and lopinavir led to a treatment that was 6.5 times more effective than the limited effects of remdesivir alone.

United statesNational university of singaporeSingapore generalEmily hendersonAgata blasiakInstitute for healthDepartment of biomedical engineeringDrug administrationInstitute for digital medicine wisDepartment of pharmacologyShanghai jiao tong universityCancer science institute of singaporeSenior research fellow in prof hoNational universityUnited states foodDigital medicine