High CO2 is a good proxy for poor ventilation. This little instrument looks like it could be useful.
“A Reader’s Guide to Safety & Adverse Event Data From Vaccine Trials” [Hilda Bastian, PLOS]. Lots of good tips. Here’s one: “Solicited adverse events are a list of events/symptoms that participants are specifically asked to record. If that’s not done in a consistent, structured way, the rate of adverse events is likely to be under-estimated. The less thoroughly researchers look, the fewer they’ll find – and the rate of adverse events they report could be artificially low. A vaccine trial should have a structured method for soliciting adverse events for the week after vaccination, either for everyone, or for a large enough representative subset of people. That’s because vaccines stimulate the immune system, and that stimulation can cause a well-known set of adverse reactions (called reactogenicity). Normal immune reactions are transient, which means they go aw