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Clinical Benefit and Regulatory Outcomes of Cancer Drugs Receiving Accelerated Approval

This study aims to determine whether cancer drugs granted accelerated approval from the US Food and Drug Administration ultimately demonstrate clinical

United statesSan diegoAarons kesselheimCommonwealth fundAmerican association for cancer research annual meetingDivision of pharmacoepidemiologyNational clinical trialLeukemia lymphoma societyDrug administrationEuropean organisation for researchSection refKey regulatoryData extractionApproval determinationsQuality of life dataGoogle scholar

International Consensus Criteria for Pediatric Sepsis and Septic Shock

This article revises criteria to identify sepsis in children after an exhaustive process that involved, surveying clinicians, reviewing health record databases,

United statesUnited kingdomSouth africaSand pointDerekc angusR scott watsonChristopher seymourCliffords deutschmanLynn retfordKathy vermochLori harmonMedicina intensiva brasileira flauzinoRebeca mozunCenters for diseaseAmerican college of chest physiciansEuropean society of intensive care medicine

Reporting of Factorial Randomized Trials

This article provides an extension of the Consolidated Standards of Reporting Trials 2010 checklist for the reporting of factorial trials.

City ofUnited kingdomBrennanc kahanClinical trials unit at university college londonResearch councilUnited kingdom office for national statisticsUnited kingdom national institute for healthNational institute of health researchBetter researchCare researchTransparency of health researchConsolidated standardsReporting trialsHealth researchSection refTerms used

As Semaglutide s Popularity Soars, Rare but Serious Adverse Effects Are Emerging | Gastroenterology | JAMA

This Medical News article discusses Wegovy, Ozempic, and other GLP-1 receptor agonists used for weight management and type 2 diabetes.

University of texas southwestern medical centerUnited statesUnited kingdomBritish columbiaGirishp joshiMahyar etminanSusan yanovskiKasia lipskaEli lillyEuropean medicines agencyYale school of medicineNovo nordiskNational institute of diabetesUniversity of british columbiaResearch letterDrug administration

Hepatitis C in Black Individuals in the US

This review summarizes evidence regarding Black race and inequities in outcomes of hepatitis C virus (HCV) infection because of the high prevalence and absolute

United statesDistrict of columbiaNew yorkNational institutes of healthJohns hopkins universitySan franciscoMary mcgrae mcdermottOluwaseun falade nwuliaFrancis collinsNovo nordiskAbbvie incUs preventive services taskGilead sciencesMasonf lord center towerGlaxosmithkline to johns hopkins universityJohns hopkins university school of medicine

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