Malaria trial shows striking 70% reduction in severe illness in children | Global health
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Drug and vaccine combo could cut child malaria deaths by 70 per cent, study shows
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Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial
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This article is based on research findings that are yet to be peer-reviewed. Results are therefore regarded as preliminary and should be interpreted as such. Find out about the role of the peer review process in research
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Researchers from the University of Oxford and their partners have today reported findings from a Phase IIb trial of a candidate malaria vaccine, R21/Matrix-M, which demonstrated high-level efficacy of 77% over 12-months of follow-up. In their findings (posted on SSRN/Preprints with
The Lancet) they note that they are the first to meet the World Health Organization s Malaria Vaccine Technology Roadmap goal of a vaccine with at least 75% efficacy.