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Scancell picks lead COVID-19 vaccine candidate

Scancell picks lead COVID-19 vaccine candidate 18th December 2020 UK-based Scancell Holdings has selected a lead COVID-19 vaccine candidate – SN14 – to advance through further development and into clinical trials. Scancell’s DNA vaccines target dendritic cells to stimulate high avidity T cells that identify and destroy diseased cells. This technology has been successfully applied with Scancell’s lead ImmunoBody cancer vaccine, SCIB1, which was safely administered to patients with malignant melanoma in a phase I/II clinical trial with “outstanding five-year survival,” according to the firm. Scancell aims to use this technology platform to produce a simple, safe, cost-effective and scalable vaccine that induces both durable T cell responses and virus neutralising antibodies (VNAbs) to provide long-lasting immunity against COVID-19.

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