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Two studies seek to go beyond GIST of intestinal tract cancer
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Chatter Between Cell Populations Drives Progression of Gastrointestinal Tumors
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IMAGE: Jason Sicklick, MD, professor of surgery at UC San Diego School of Medicine and surgical oncologist at UC San Diego Health. view more
Credit: UC San Diego Health Sciences
Gastrointestinal stromal tumors (GISTs) are a subytpe of cancers known as sarcomas. GIST is the most common type of sarcoma with approximately 5,000 to 6,000 new patient cases annually in the United States. GIST cannot be cured by drugs alone, and targeted therapies are only modestly effective, with a high rate of drug resistance. In a recent study, researchers at University of California San Diego School of Medicine and Moores Cancer Center identified new therapeutic targets that could lead to new treatment options for patients.