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A new way of treating major depression has been developed by scientists at the University of California San Francisco (UCSF). The approach builds on earlier work that identified signature electrical activities in the brain that correlate to different moods, and brain regions that when stimulated relieve depression. In the new two-step method, the researchers identify a symptom-specific neural biomarker and a treatment location where focal electrical stimulation improves the symptoms. They then implant a device in the identified location, capable of sensing and stimulating electrical impulses that triggers therapeutic deep brain stimulation when the severity of the symptom increases.

Edward changSanford weillKatherine scangosAndrew krystalWeill instituteBrain researchUniversity of california san franciscoWeill institute for neurosciencesInnovative neurotechnologies initiativeCalifornia san franciscoNature medicinePresident obamaAdvancing innovative neurotechnologiesSanford weill chair