Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP.
Prion diseases are associated with the formation of aggregates of the prion protein, PrP, yet how these aggregates form are not fully understood. Now, researchers suggest the aggregates kill neurons by damaging their axons.