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Samantha Giffen, PhD ’21, loves the thrill of discovery, in the lab and beyond May 6, 2021 – One day in 2014, Samantha Giffen sat in a small dark room at the New York State Department of Public Health’s Wadsworth Center, peering at the screen of a hulking electron microscope. She and a colleague had set up an experiment to test whether an antibody known as ZAC-3 would have any effect on Vibrio cholerae, the bacterium that causes cholera, a deadly diarrhoeal disease that afflicts millions of people in poor countries. As the image came into focus, Giffen could see that the bacteria’s outer membranes were crumpled and their tail-like flagella were coiled, signs that the antibody had vanquished the pathogen.

United statesSouth africaNew jerseyUniversity of massachusettsSamantha giffenCenters for diseaseProgram in biological sciences public healthUniversity of massachusetts amherstNational science foundationDepartment of immunologyUniversity of north carolina chapel hillNew york state departmentPublic healthWadsworth centerBiological sciencesDisease control