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Subgroup analyses from non–small cell lung cancer clinical trials, such as the phase 3 POSEIDON and FLAURA2 trials, can help personalize treatment decisions with immunotherapy and targeted therapy based on individual mutational profiles.

United statesUniversity of arkansasKonstantinos arnaoutakisSanjay maraboyinaAhmed mazen safarSarahw jewellSajjada bhattiDepartment of radiation oncologyEuropean society for medical oncology congressDepartment of internal medicineDivision of hematologyWinthropp rockefeller cancer instituteRadiation oncology networkInstitutional perspectivesInternal medicineMedical sciences