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Introduction Comprehensive local data on adolescent health are often lacking, particularly in lower resource settings. Furthermore, there are knowledge gaps around which interventions are effective to support healthy behaviours. This study generates health information for students from cities in four middle-income countries to plan, implement and subsequently evaluate a package of interventions to improve health outcomes. Methods and analysis We will conduct a cluster randomised controlled trial in schools in Fez, Morocco; Jaipur, India; Saint Catherine Parish, Jamaica; and Sekondi-Takoradi, Ghana. In each city, approximately 30 schools will be randomly selected and assigned to the control or intervention arm. Baseline data collection includes three components. First, a Global School Health Policies and Practices Survey (G-SHPPS) to be completed by principals of all selected schools. Second, a Global School-based Student Health Survey (GSHS) to be administered to a target sample of n=3

Saint catherine parishSaint catherineRabat saléemmour zaëmoGlobal school health policiesResearch ethics review committeeMinistry of healthGlobal student health surveyLegal affairs for st catherine parishPractices surveySchoola health promoting schoolWellnes advisory panel on ethicsGlobal school based student health surveyMaking every schoolHealth promotingEthics review committeeJodhpur school