We are just getting some breaking news from president obama. He is giving a News Conference in manila right now. Lets listen in. He is talking about sanctions in russia. Relief operations, i will give you a perfect example. Sprey aircraft, a significant upgrade in capabilities in caves in terms of reaching out to remote areas. About thealking missing malaysia and aircraft, the president listening to what is being said in manila. He has been talking about the situation visavis russia. Pfizer has confirmed a possible offer for astrazeneca. With more on that story, manus cranny and sam from bloomberg industries. Lets start with you, sam. What do we know at this point and what dont we know . We know that pfizer made an approach in january. On the 16th of april, they came back again. As you and i were talking last week after the Novartis Glaxosmithkline deal, that might have tweaked their interest again. There are many other regions where pfizer would be interested in an astrazeneca. That i