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UAB researchers identify cell-surface marker that indicates fate of T cells

Follicular helper T cells, or Tfh cells, have a crucial role in immune defense. Without Tfh cells, B cells cannot form germinal center, or GC, responses during which high-affinity antibodies are generated.

United statesLa jollaDiegoo sialerRyanj mcmonigleDavid figgeKellym chandlerAdamj getzlerYohsuke haradaMatthewe pipkinAndrewr schroederLily ramseyOlaf kutschFangming zhuEmilyr brownBraxtond greerXianyou xia

A fate determination fork-in-the-road for germinal center Tfh and T memory cells

Some PD-1+CXCR5+CD4+ T cells will become germinal center-Tfh cells that are essential for B cells to become high-affinity antibody-producing cells. Others do not take that path, instead becoming memory T cells. Fangming.

United statesLa jollaSteve woodhuSteve woodfollicularMatthewe pipkinAndrewr schroederAdamj getzlerOlaf kutschDiegoo sialerXianyou xiaYohsuke haradaBraxtond greerFangming zhuRyan mcmonigleEmilyr brownDavid figge

Determining Fate of Tfh and T Memory Cells in Germinal Center

Determining Fate of Tfh and T Memory Cells in Germinal Center
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

La jollaUnited statesYohsuke haradaDavid figgeEmilyr brownOlaf kutschMatthewe pipkinAndrewr schroederKellym chandlerBraxtond greerDiegoo sialerXianyou xiaFangming zhuRyanj mcmonigleAdamj getzlerDepartment of pathology

A fate determination fork-in-the-road for germinal center Tfh and T memory cells

A fate determination fork-in-the-road for germinal center Tfh and T memory cells
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

Ryanj mcmonigleFangming zhuNature communicationsDepartment of microbiologyUniversity of alabama at birminghamSustained tigit