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The use of topical imiquimod was found to effectively promote regression of precancerous cervical lesions, according to a phase II randomized controlled trial.
In a per-protocol population of women with high-grade squamous intraepithelial lesions (HSIL) of the cervix, histologic regression of lesions was observed in 60.5% of patients receiving weekly treatment with imiquimod compared with just 22.5% in the control group (
P=0.001), resulting in a number needed to treat (NNT) of 2.63, reported Bruno O. Fonseca, MD, of Barretos Cancer Hospital in São Paulo, Brazil, and colleagues.
HSIL of the cervix, which are induced by human papillomavirus (HPV), are a precursor to cervical cancer. The standard treatment is surgical excision by either cold knife conization, laser conization, or a loop electrosurgical excision procedure (LEEP).
What parents need to know about mask guidance and unvaccinated children TODAY 3 hrs ago Meghan Holohan
When the Centers for Disease Control and Prevention released guidelines saying it is safe for fully vaccinated Americans to go without a mask in most situations, many sighed in relief and happily cast their masks aside.
But parents with children who are too young for a COVID-19 vaccine wonder what this means for them: Should they continue to wear masks in public places? Do they need to keep their children away from the grocery store, Target or movie theaters?
“Parents should encourage masking and they should avoid crowded public spaces,” Dr. Sten Vermund, dean of the Yale School of Public Health in New Haven, Connecticut, told TODAY. “So that’s it in a nutshell.”
Experts are, therefore, urging people to improve ventilation in order to reduce the spread of the virus
Still, fomite transmission, i.e. through contaminated surfaces or objects, cannot be entirely ruled out
In the early days of the Covid-19 pandemic, public health guidance was largely based on what we knew about past disease outbreaks. To reduce our risk of infection, we were advised to disinfect potentially contaminated surfaces or objects, known as fomites, such as doorknobs and tabletops, as these were thought to be one of the main ways through which one could contract the virus.
Over more than a year, however, scientists have learned a lot more about SARS-CoV-2, the virus that causes Covid disease, and increasing evidence suggests that our focus should instead shift to preventing airborne transmission.
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Ask ten people what meditation is, and you might get ten answers but they could all be right. It’s a practice that dates back thousands of years and has been part of so many cultures that there are now dozens of ways to do it. Still, they share an underlying similarity: “It’s a practice that cultivates inward investigation,” says Diana Winston, director of Mindfulness Education at UCLA’s Mindful Awareness Research Center.
What accounts for meditation’s lasting and widespread appeal? The answer may lie in a growing body of research that confirms what many practitioners have claimed for years: Meditation has been shown to be helpful taming stress and anxiety, reducing cardiovascular risk factors, managing chronic pain, and improving sleep
Weeks after New Jersey began distributing COVID vaccines, Lynne Algrant got a call from Bergen New Bridge Medical Center.
The Paramus hospital, nestled in a county where minorities make up almost half the population, was struggling to sign up nonwhite patients for the shots.
At the same time, Algrant, vice president of a Hackensack nonprofit that works with low-income families, was being peppered by calls from Black, Latino and Asian residents struggling to get coveted vaccines. We thought we were going to be facing hesitancy, and we thought we were going to need to do a lot of community education, said Algrant, who works for Greater Bergen Community Action. What we found very quickly is that people couldn t find appointments and couldn t navigate the system.