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Researchers create an innovative tool for the reliable and efficient study of gene function

A team of scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) led by Rui Benedito has generated a novel genetic tool, called iSuRe-HadCre, that enables the induction of precise genetic alterations in whole tissues or in individual cells with high efficiency and reliability. This new technology is set to become an important tool in biomedical research that uses mouse models to modify and understand gene function.

Científicos descubren mecanismo celular y molecular para la recuperación de arterias dañadas

Científicos descubren mecanismo celular y molecular para la recuperación de arterias dañadas
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Desvelado un nuevo mecanismo para el desarrollo de las arterias

Desvelado un nuevo mecanismo para el desarrollo de las arterias
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A New Mechanism to Develop Arteries

A New Mechanism to Develop Arteries December 10, 2020 A recent study reveals a new cellular and molecular mechanism essential for the process of arterialization the development of arteries from blood capillaries. Activation of this mechanism could improve the recovery of heart function after transient or long-term reduction in heart blood flow. From left to right: Verónica Casquero, Sofía Sánchez, Irene García, Macarena Fernández, Wen Luo, Severin Muhleder, Lourdes García, Rui Benedito. [CNIC] The research, done by a group at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid, Spain, not only advances understanding of the biology of blood vessels, but also points the way to the design of new therapeutic strategies to induce vascularization and more effective blood perfusion of injured or ischemic tissues.

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