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/PRNewswire/ Collagen Matrix, Inc. ("Collagen Matrix"), a global leader in regenerative medicine and a Linden Capital Partners ("Linden") portfolio company,.
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Polyganics, a medical technology company developing, manufacturing and commercializing bioresorbable medical devices, today announced treatment of the first patient in its ENCASE II clinical trial for LIQOSEAL
®.
LIQOSEAL
® is an easy-to-use, synthetic dura sealant patch indicated for use as an adjunct to standard methods of cranial dural repair, to provide watertight closure of the dura mater and reduce cerebrospinal fluid (CSF) leakage. In addition, LIQOSEAL
® also supports regeneration of the dura mater by acting as a scaffold for new fibrotic layer formation (‘neodura’).
ENCASE II is randomized, two-arm, multicenter study, evaluating the safety and efficacy of LIQOSEAL
® in reducing intra- or post-operative CSF leakage in patients undergoing elective cranial surgery. The trial will involve 228 patients, enrolled and treated at up to 20 clinical centres across the US and Europe. Patients wi