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Crossing the barrier: Breakthrough in drug delivery could help fight against brain cancer, disorders

Researchers captured world-first images of the antibody therapy drug, Trastuzumab, targeting tumours that spread to the brain from breast cancer.

Kullervo hynynenRossanna pezoNir lipsmanSunnybrook research instituteSunnybrook health sciences centreLevel disease burden initiativeScience translational medicineVice president innovationSunnybrook researchIndia state level disease burden initiativeLancet global healthBrain cancerNeurological disordersDrug deliveryCience newsMedical breakthrough

Ultrasound Delivers Antibody Therapy to Breast Cancer Metastases in the Brain

Clinical trial data demonstrate that focused ultrasound can be used to safely deliver antibody therapy to breast cancer that has metastasized to the brain.

Rossanna pezoNir lipsmanOdette cancer centre at sunnybrookExablate neuroScience translational medicineHarquail centreSunnybrook health sciences centreOdette cancer centre

MR-guided focused ultrasound can safely deliver antibody therapy to Her2-positive brain metastases

In a first-in-world clinical trial, researchers at Sunnybrook Health Sciences Centre in Toronto, Canada, have demonstrated that magnetic resonance (MR)-guided focused ultrasound can be used to safely deliver antibody therapy to breast cancer that has metastasized to the brain.

Rossanna pezoNir lipsmanNealf kassellEmily hendersonOdette cancer centre at sunnybrookUltrasound centerUltrasound foundationSunnybrook health sciences centreHarquail centre for neuromodulation at sunnybrookExablate neuroHarquail centreScience translational medicineOdette cancer centreFocused ultrasound centerFocused ultrasound foundationBreast cancer

World-first Clinical Trial Demonstrates Focused Ultrasound Can Deliver Antibody Therapy to Breast Cancer Metastases in the Brain

Researchers at Sunnybrook Health Sciences Centre published results Oct. 13 in Science Translational Medicine

Rossanna pezoNir lipsmanNealf kassellOdette cancer centre at sunnybrookUltrasound centerUltrasound foundationSunnybrook health sciences centreHarquail centre for neuromodulation at sunnybrookExablate neuroHarquail centreScience translational medicineOdette cancer centreFocused ultrasound centerFocused ultrasound foundation

Ultrasound delivers antibody therapy for HER2-positive brain metastasis

Ultrasound delivers antibody therapy for HER2-positive brain metastasis
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Rossanna pezoNir lipsmanSunnybrook health sciences centreScience translational medicineExablate neuro