New study unravels complete sequence of DNA repair mechanism
Every living organism has DNA, and every living organism engages in DNA replication, the process by which DNA makes an exact copy of itself during cell division. While it s a tried-and-true process, problems can arise.
Break-induced replication (BIR) is a way to solve those problems. In humans, it is employed chiefly to repair breaks in DNA that cannot be fixed otherwise. Yet BIR itself, through its repairs to DNA and how it conducts those repairs, can introduce or cause genomic rearrangements and mutations contributing to cancer development. It s kind of a double-edged sword, says Anna Malkova, professor in the Department of Biology at the University of Iowa, who has studied BIR since 1995. The basic ability to repair is a good thing, and some DNA breaks can t be repaired by other methods. So, the idea is very good. But the outcomes can be bad.
Biologists unravel full sequence of DNA repair mechanism
Biologists unravel full sequence of DNA repair mechanism Photo by Daniil Kuzelev/Unsplash.
By: Richard C. Lewis | 2021.01.25 | 10:02 am
Every living organism has DNA, and every living organism engages in DNA replication, the process by which DNA makes an exact copy of itself during cell division. While it’s a tried-and-true process, problems can arise.
Break-induced replication (BIR) is a way to solve those problems. In humans, it is employed chiefly to repair breaks in DNA that cannot be fixed otherwise. Yet BIR itself, through its repairs to DNA and how it conducts those repairs, can introduce or cause genomic rearrangements and mutations contributing to cancer development.
Lowestoft folk hero John Ward has composed The Light Returns to celebrate the festival s themes of day and night, the sea and the elements, and the history and future of the town.
Lowestoft s Rogue Shanty Buoys will also perform a version of the song along with community singers from the Pakefield Singers.
The First Light Festival s Winter Solstice event will be streamed online from December 20.
- Credit: First Light Festival
Choreographer Rosemary Lee s Dusk Dance has been inspired by folk traditions of men dancing together on the winter solstice and will take place against the falling night sky over the North Sea.
Published:
6:52 PM December 15, 2020
The Wheel art installation on Lowestoft s South Beach will be a focal point of First Light Festival s celebration of the Winter Solstice
- Credit: First Light
Suffolk’s east coast arts festival First Light is marking the end of a unique year with a series of specially-commissioned online winter solstice performances.
The festival, which is based in and around Lowestoft, will be marking the shortest day of the year with a number of online winter solstice events designed to remind people that after a challenging year brighter, lighter days are just around the corner.
The Wheel will send out message of hope at the conclusion of the Winter Solstice celebrations which can be viewed online on Sunday December 20