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Jun 9, 2021
Simulation reflected a trial with no treatment effect
Variability in individual cognitive trajectories may be why cognitive results in most Alzheimer’s disease (AD) trials fell within the level of random differences that occur when no treatment effect is expected, a simulation study showed.
“Our simulation reflects a clinical trial in which there is no real treatment effect, and so the 95% range of group differences between our ’placebo’ and ’treatment’ groups reflect the possible range of scores that can be expected when there is no treatment effect,” wrote Roos Jutten, PhD, of Amsterdam UMC in the Netherlands, and co-authors, in