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Participants given omadacycline had high fecal concentrations with a distinct microbiome profile compared to those in the vancomycin group, with study results calling attention to the importance of antibiotics’ impact on the gut microbiome.

United statesKevin gareyRobertl boblittUniversity of houston college pharmacyUs centers for diseaseUniversity of houston kevin gareyUniversity of houstonRobertl boblitt endowed professorDrug discoveryHouston collegeDisease controlGut microbiome effectsOral omadacycline versus vancomycinHealthy volunteersInfectious diseasesC diff