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s Independent financial analysts widely recognize this progress: “ZIOP continues to make progress with respect to the company-sponsored TCR-T program, the Controlled IL-12 program, and the Sleeping Beauty CAR-T program.” 2 “By unlocking the potential of its Sleeping Beauty technology, the Company is poised to deliver a leap forward in the personalization of cancer therapy.” 3 “We think that the company continues to make forward progress across its various platforms (TCR-T, CAR-T, and controlled IL-12).ZIOP has executed well over 2020 in curating immune receptors from its own libraries and it is moving forward its wholly owned program.” 4 The Company continues to urge shareholders to support Ziopharm’s continued progress and protect the value of their investment by signing and returning the

United statesChris kittredgeRaymond jamesZachary tramontiAndrew coleMichael verrechiaHolger weisJ kevin buchiJaime vieserRobertw postmaRobert postmaServices egan jonesZiopharm oncology incNational cancer instituteUniversity of texas md anderson cancer centerWatermill asset management corp