Researchers say a clinical trial has shown how important it is to diagnose asthma and COPD early to provide effective treatments and improve a person's quality of life
Target Audience and Goal Statement: Neurologists
The goal of this study was to assess a diagnostic test that stratifies epileptic seizures from psychogenic non-epileptic seizures (PNES) by developing a multimodal algorithm that integrates plasma concentrations of selected immune response-associated proteins and patient clinical risk factors for seizure.
Question Addressed:
Study Synopsis and Perspective:
Epilepsy affects over 70 million people worldwide. This common brain condition has multiple risk factors and a strong genetic predisposition.
Action Points
Four immune response-associated proteins TRAIL, ICAM-1, MCP-2, and TNF-R1 distinguished psychogenic non-epileptic seizures (PNES) from epileptic seizures with sensitivity of 82.6% and specificity of 91.6% when analyzed in a diagnostic algorithm, according to a recent small study.
Target Audience and Goal Statement: Pulmonologists, primary care physicians
The goal of the updated U.S. Preventive Services Task Force (USPSTF) recommendation statement was to evaluate the benefits and harms of primary care interventions on tobacco use cessation in adults, including pregnant persons.
Question Addressed:
What were the benefits and harms of primary care interventions on tobacco use cessation in adults, including pregnant persons?
Synopsis and Perspective:
In 1964, the U.S. Surgeon General released a report concluding that cigarette smoking was a cause of lung cancer in men, a probable cause of lung cancer in women, and the most important cause of chronic bronchitis. More than half a century later, another report was issued concluding that smoking cessation decreased the risk of all-cause mortality, cardiovascular diseases, chronic obstructive pulmonary disease, adverse reproductive health outcomes, and 12 types of cancer.