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Adcendo presents Data on uPARAP targeting ADCs in Osteosarcoma PDX Models at the 2022 AACR Annual Meeting

MD Anderson and Houston Dynamo FC team up to kick childhood cancer

MD Anderson and Houston Dynamo FC team up to kick childhood cancer
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Researchers identify surface protein as a new osteosarcoma therapeutic target for antibody-drug conjugates

 E-Mail IMAGE: A preclinical study shows an antibody-drug conjugate (ADC) targeting surface protein MT1-MMP can act as a guided missile in eradicating osteosarcoma tumor cells without damaging normal tissues. This technology, using. view more  Credit: MD Anderson Cancer Center Abstract #LB008 HOUSTON A preclinical study led by researchers at The University of Texas MD Anderson Cancer Center shows an antibody-drug conjugate (ADC) targeting surface protein MT1-MMP can act as a guided missile in eradicating osteosarcoma tumor cells without damaging normal tissues. This technology, using precision therapy targeting of cell-surface proteins through a Bicycle toxin conjugate (BTC), shows encouraging results for the treatment of osteosarcoma.

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