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Genetic Links Between Traits Often Overstated?

Many estimates of how strongly traits and diseases share genetic signals may be inflated, according to a new UCLA-led study that indicates current methods for assessing genetic relationships between traits fail to account for mating patterns.

Health News | Genetic Links Between Traits Often Overstated: Research

Get latest articles and stories on Health at LatestLY. Genetic correlation estimates typically assume that mating is random. But in the real world, partners tend to pair up because of many shared interests and social structures. Health News | Genetic Links Between Traits Often Overstated: Research.

Genetic links between traits often overstated: Research

Estimates of genetic correlation often presume that mating is random

Cross-trait assortative mating may bias genetic correlations and pleiotropic effects

Cross-trait assortative mating may bias genetic correlations and pleiotropic effects
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Non-Random Mating May Exaggerate Findings of Pleiotropy in Population Genetic Studies

Researchers saw signs that cross-trait assortative mating can explain a range of genetic correlation events, leading to overestimates of the contributions of genetic factors.

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