3D cell culture and organoids: Potential tools in the fight against COVID-19 Dr. Shuibing Chen discusses the advantages of organoids, surprising discoveries in COVID research, and her hopes for revolutionizing the future of drug therapies. Read article
A novel target to inhibit glioblastoma invasion Dr. Aleksandra Dukic, Oslo University Hospital, describes a novel target for inhibiting glioblastoma cancer invasion into surrounding brain tissue and the importance of this work in addressing the need for innovative therapeutics to combat this aggressive cancer. Watch on The Scientists Channel
Analyzing cancer progression and treatment efficacy with imaging mass spectrometry Dr. Amanda Hummon, Ohio State University, explains how her research group is developing novel mass spectrometry methods to examine the interaction between drugs and cancer samples in both 3D cell cultures and patient-derived organoids. Watch on The Scientists Channel
3D cell culture and organoids: Potential tools in the fight against COVID-19 Dr. Shuibing Chen discusses the advantages of organoids, surprising discoveries in COVID research, and her hopes for revolutionizing the future of drug therapies. Read article
A novel target to inhibit glioblastoma invasion Dr. Aleksandra Dukic, Oslo University Hospital, describes a novel target for inhibiting glioblastoma cancer invasion into surrounding brain tissue and the importance of this work in addressing the need for innovative therapeutics to combat this aggressive cancer. Watch on The Scientists Channel
Analyzing cancer progression and treatment efficacy with imaging mass spectrometry Dr. Amanda Hummon, Ohio State University, explains how her research group is developing novel mass spectrometry methods to examine the interaction between drugs and cancer samples in both 3D cell cultures and patient-derived organoids. Watch on The Scientists Channel
Editorial Article: Organoid-based 3D model of human glioblastoma: Recreating brain tumors in a dish
Discover how a brain organoid core facility is applying its glioblastoma model towards developing patient mini-brains
08 Apr 2021
Glioblastoma, the deadliest of primary brain tumors in adults, has a median survival of only about 15 months, with less than 6% of patients surviving past the five-year mark. The urgent need to fully understand the cancer biology of glioblastoma is thwarted by the lack of a suitable disease model that mimics the cerebral microenvironment.
Dr. Richa Singhania, Director of the Starr Foundation Glionoid Translational Core at Weill Cornell Medicine
In recent times, cerebral organoids, the self-assembling three-dimensional cellular models derived from stem cells, have opened up the possibility of replicating the brain’s milieu to closely examine and study glioblastomas.