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Post SCT, Better Survival in Kids With Healthy Gut Diversity

Pediatric patients receiving a donor stem cell transplant who have healthier pretransplant gut microbiota diversity show improved rates of survival and a lower risk of acute GvHD.

United statesRiccardo masettiProlacta biosciencesRobert jenqUniversity of bolognaCancer centerSeres therapeuticsTransplantation stem cellRansplantation hematopoietic stem cellHematopoietic stem cell transplantationStem cell transplantationStem cell therapyHerapy stem cellSocial determinants of healthBiologic therapyC diff infection

Diverse gut microbiome may help children survive stem cell transplant

Researchers in Italy have shown for the first time that among children who have undergone a donor stem cell transplant, the presence of diverse species of micro-organisms in the intestinal tract before the transplant resulted in significantly better overall patient survival and fewer complications.

Riccardo masettiDanielle ellisUniversity of bolognaDepartment of pediatric oncologyPediatric oncology

Enhanced gut microbiome diversity linked to improved survival in children receiving stem cell transplants

Enhanced gut microbiome diversity linked to improved survival in children receiving stem cell transplants
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Riccardo masettiUniversity of bolognaDepartment of pediatric oncologyPediatric oncology

Gut Microbiome Diversity Boosts Survival in Pediatric Stem Cell Transplant Recipients

Pioneering research reveals correlation between intestinal tract microbiota diversity and survival in kids who have received a donor stem cell transplant.

Riccardo masettiDepartment of pediatric oncologyUniversity of bolognaPediatric oncologyStem cell transplantGut microbiome

Gut Microbiota Diversity Linked to Better Survival After Pediatric HSCT

Patients with higher diversity also had lower rates of acute graft-versus-host disease

United statesRiccardo masettiMike bassettUniversity of bologna

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