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Racial Discrimination Affects Brain Microstructure

In Black women, racial discrimination affects the microstructure of the brain, specifically within the anterior cingulum bundle and corpus callosum, and increases adverse mental health risks.

Brain functional connectivity in Tourette syndrome

 E-Mail Philadelphia, July 7, 2021 - Tourette syndrome, a neurodevelopmental disorder, causes motor and phonic tics or uncontrollable repeated behaviors and vocalizations. People affected by Tourette syndrome can often suppress these tics for some time before the urges become overwhelming, and researchers have long wondered at the neural underpinnings of the suppression effort. Now, in a new study using a non-invasive technique to measure brain activity called high-density electroencephalography (hdEEG), researchers at Yale School of Medicine have assessed the impact of tic suppression on functional connectivity between brain regions. The study appears in Tic suppression is an important feature of Tourette syndrome. Understanding how someone may temporarily gain control over their tics may inform several research areas in Tourette syndrome. Yet, brain correlates of tic suppression have not been studied extensively, especially in children, said Denis Sukhodolsky, PhD, senior

Antidepressants safe during pregnancy

Antidepressants safe during pregnancy
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Childhood disadvantage affects brain connectivity

In a new study, researchers have examined how neighborhood disadvantage and how it can affect the developing brain, including the brain s connectivity between regions. The study appears in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, published by Elsevier.

Estrogen status - not sex - protects against heightened fear recall

 E-Mail Philadelphia, April 15, 2021 -A new study shows that markers of fear recall differ between men and women, but in a hormone-dependent manner. Aberrant fear-memory processing in the brain is thought to underlie anxiety disorders, which affect hundreds of millions of people worldwide. The neurobiological mechanisms underlying these disorders remain poorly understood, but recent studies suggest that neural oscillations in the prefrontal cortex can reflect the strength of fear recall activity, providing a physiological measure. Women suffer from anxiety disorders at twice the rate of men and indeed the literature shows that there are sex differences in fear recall behaviors, but this area of study has not been extended to neural oscillations. Additional studies suggest a modulatory role for the female sex hormone estradiol (E2) for fear recall and extinction recall.

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