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Therapeutic advances in rheumatoid arthritis

Rheumatoid arthritis (RA) is one of the most common immune mediated inflammatory diseases. People with rheumatoid arthritis present with pain, swelling, and stiffness that typically affects symmetrically distributed small and large joints. Without effective treatment, significant joint damage, disability, and work loss develop, owing to chronic inflammation of the joint lining (synovium). Over the past 25 years, the management of this condition has been revolutionized, resulting in substantially higher levels of disease remission and better long term outcomes. This improvement reflects a paradigm shift towards early and aggressive pharmacological intervention coupled with a proliferation in treatment choice, in turn related to enhanced pathobiological understanding and the advent of new drugs for rheumatoid arthritis. Following an overview of these developments from a historical perspective, and with a general audience in mind, this review focuses on newer, targeted treatments in an ev

Incidence, Prevalence, and Mortality of Dermatomyositis in Adults Determined

Dual-Energy CT Accurately Diagnoses Urate Crystal Deposition in Gout; Limited Sensitivity for Short-Stage Gout

Dual-Energy CT Accurately Diagnoses Urate Crystal Deposition in Gout; Limited Sensitivity for Short-Stage Gout
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