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In this application note, RETSCH GmbH discusses the importance of sample preparation for various biological materials. They offer a range of mills and grinders for pulverization, cell disruption, and homogenization of biological samples. The article highlights the use of RETSCH mills for applications such as cell disruption of yeasts, microalgae, and bacteria, homogenization of soft and tough samples like sputum or liver, cryogenic grinding, and pulverization of forensic samples.