Researchers identify a common mechanism underlying diverse brain disorders
Researchers at Vanderbilt University Medical Center (VUMC) have identified a common mechanism underlying a spectrum of epilepsy syndromes and neurodevelopmental disorders, including autism, that are caused by variations in a gene encoding a vital transporter protein in the brain.
Their findings, reported last month in the journal
Brain, suggest that boosting transporter function via genetic or pharmacological means could be beneficial in treating brain disorders linked to these genetic variations.
This points to a clear direction of treating a wide spectrum of neurodevelopmental disorders, from various epilepsy syndromes (and) autism to neurodevelopmental delay and intellectual disabilities, caused by the pathological variants in this gene.
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IMAGE: Jing-Qiong (Katty) Kang, M.D., Ph.D., associate professor of Neurology and Pharmacology, Vanderbilt University Medical Center. view more
Credit: Vanderbilt University Medical Center
Researchers at Vanderbilt University Medical Center (VUMC) have identified a common mechanism underlying a spectrum of epilepsy syndromes and neurodevelopmental disorders, including autism, that are caused by variations in a gene encoding a vital transporter protein in the brain.
Their findings, reported last month in the journal
Brain, suggest that boosting transporter function via genetic or pharmacological means could be beneficial in treating brain disorders linked to these genetic variations. This points (to) a clear direction of treating a wide spectrum of neurodevelopmental disorders, from various epilepsy syndromes (and) autism to neurodevelopmental delay and intellectual disabilities, caused by the pathological variants in this gene, said Jing-Qiong (Katty) Kan
Antibody cocktails effective against SARS-CoV-2 variants
Written by Timothy Huzar on March 11, 2021 â Fact checked by Mary Cooke, Ph.D.
Numerous therapeutics have been developed to treat COVID-19.
However, many are based on initial variants of SARS-CoV-2 and may be less effective against recent ones.
In the present study, researchers have identified monoclonal antibody âcocktailsâ that are still effective against recent variants.
All data and statistics are based on publicly available data at the time of publication. Some information may be out of date. for the most recent information on the COVID-19 pandemic.
In laboratory tests, a team of researchers has analyzed the efficacy of a range of COVID-19 antibody-based therapeutics against the latest variants of SARS-CoV-2.
Researchers develop antibody cocktail effective against all Covid-19 strains thehindubusinessline.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from thehindubusinessline.com Daily Mail and Mail on Sunday newspapers.
Over 20 dead, millions struggle without power as cold snap grips US
Agencies
February 17, 2021
Washington, Feb 17: Millions were left without power as a winter storm gripped the southern and central United States on Tuesday with record-low temperatures in ill-prepared areas, and a tornado claiming three lives.
More than 20 storm-related deaths have been registered so far, including in traffic accidents in Texas, Kentucky and Missouri, according to local media.
In hardest-hit Texas where freezing conditions prompted utility companies to implement rotating blackouts a woman and girl died from carbon monoxide poisoning after using a car to generate heat, according to NBC News.