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European Ancestry Genetic Studies Possibly Inaccurate

European Ancestry Genetic Studies Possibly Inaccurate
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United statesCharles rotimiMateus gouveiaDaniel shrinerGlobal healthNational institutes of healthResearch on genomicsNature communicationsNational human genome research instituteNational institutesEuropean americans

Previous genetic association studies involving people with European ancestry may be inaccurate

Previous genetic association studies involving people with European ancestry may be inaccurate
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United statesCharles rotimiMateus gouveiaDarryl lejaDaniel shrinerResearch on genomicsNational human genome research instituteGlobal healthNational institutes of healthNature communicationsNational human genome researchNational institutesEuropean americansUnappreciated subcontinental admixtureGenetic epidemiology studies

Previous genetic association studies involvin

<p>Researchers have found that previous studies analyzing the genomes of people with European ancestry may have reported inaccurate results by not fully accounting for population structure. By considering mixed genetic lineages, researchers at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, demonstrated that previously inferred links between a genomic variant that helps digest lactose and traits such as a person’s height and cholesterol level may not be valid.</p>

United statesMateus gouveiaDaniel shrinerCharles rotimiNational institutes of healthMethod of researchNational human genome research instituteGlobal healthNature communicationsResearch on genomicsNational institutesEuropean americansSubcontinental admixtureGenetic epidemiology

Genetic Studies on European Ancestry May Be Inaccurate: NIH

Genetic Studies on European Ancestry May Be Inaccurate: NIH
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United statesCharles rotimiMateus gouveiaDaniel shrinerResearch on genomicsDepartment of healthGlobal healthNational human genome research instituteNational institutes of healthNature communicationsHuman servicesDivision of intramural researchNational institutesEuropean americansIntramural research

Inaccurate Genetic Association Studies Pose Issues for Genomic Medicine

Inaccurate Genetic Association Studies Pose Issues for Genomic Medicine
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United statesCharles rotimiMateus gouveiaDaniel shrinerNature communicationsGlobal healthResearch on genomicsNational human genome research instituteEuropean americans