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Abivax Follows DSMB Recommendation to Stop the Phase 2b/3 miR-AGE Covid-19 Clinical Trial Due to Lack of Efficacy

Press release content from Accesswire. The AP news staff was not involved in its creation. Abivax Follows DSMB Recommendation to Stop the Phase 2b/3 miR-AGE Covid-19 Clinical Trial Due to Lack of Efficacy March 5, 2021 GMT The Data Safety and Monitoring Board (DSMB) confirmed ABX464 was safe and well tolerated in 383 high-risk Covid-19 patients Lower than expected rate (10.1%) of progression to severe disease or death with no difference between ABX464 and placebo groups Decision has no impact on ABX464 development in chronic inflammatory indications ABX464 top-line clinical data expected in Q2 2021 for phase 2b ulcerative colitis trial and phase 2a rheumatoid arthritis trial

Investegate |ABIVAX Announcements | ABIVAX: Abivax follows DSMB recommendation to stop the phase 2b/3 miR-AGE Covid-19 clinical trial due to lack of efficacy

ABIVAX Abivax follows DSMB recommendation to stop the phase 2b/3 miR-AGE Covid-19 clinical trial due to lack of efficacy DGAP-News: ABIVAX / Key word(s): Study Abivax follows DSMB recommendation to stop the phase 2b/3 miR-AGE Covid-19 clinical trial due to lack of efficacy 05.03.2021 / 20:00 Abivax follows DSMB recommendation to stop the phase 2b/3 miR-AGE Covid-19 clinical trial  due to lack of efficacy The Data Safety and Monitoring Board (DSMB) confirmed ABX464 was safe and well tolerated in 383 high-risk Covid-19 patients Lower than expected rate (10.1%) of progression to severe disease or death with no difference between ABX464 and placebo groups Decision has no impact on ABX464 development in chronic inflammatory indications

Inotrem s COVID-19 Phase IIa Clinical Trial Declared National Priority Research by the French Government s Clinical Trial Council

Press release content from Business Wire. The AP news staff was not involved in its creation. Inotrem’s COVID-19 Phase IIa Clinical Trial Declared “National Priority Research” by the French Government’s Clinical Trial Council December 24, 2020 GMT PARIS (BUSINESS WIRE) Dec 24, 2020 Inotrem S.A., a biotechnology company specialized in the development of immunotherapies targeting the TREM-1 pathway, announces today that its Phase IIa study of nangibotide, the company’s lead product, for the treatment of severe forms of COVID-19 has been declared “National Priority Research” by the French government steering committee for therapeutic clinical trials and other research (CAPNET).

Investegate |ABIVAX Announcements | ABIVAX: Abivax s Covid-19 Phase 2b/3 miR-AGE trial with ABX464 declared Research National Priority by the French government s Clinical Trial Council

ABIVAX Abivax s Covid-19 Phase 2b/3 miR-AGE trial with ABX464 declared Research National Priority by the French government s Clinical Trial Council DGAP-News: ABIVAX / Key word(s): Study Abivax s Covid-19 Phase 2b/3 miR-AGE trial with ABX464 declared Research National Priority by the French government s Clinical Trial Council 22.12.2020 / 19:30 The issuer is solely responsible for the content of this announcement. Abivax s Covid-19 Phase 2b/3 miR-AGE trial with ABX464 declared Research National Priority by the French government s Clinical Trial Council Research National Priority has priority for patient enrollment in clinical trials for an accelerated review and approval process with the French regulatory authorities Effective Covid-19 treatments very much needed because optimal vaccination coverage of millions of individuals and public acceptance will take time

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