Although phase 2 data suggested baricitinib as a potential treatment for patients
with SLE, which was supported in SLE-BRAVE-I, this result was not replicated in SLE-BRAVE-II.
No new safety signals were observed.
Japan: A recent study in Arthritis Research & Therapy has shown that higher blood sugar levels in patients with radiographic knee osteoarthritis (KOA) and central sensitization (CS) are associated.
Systemic sclerosis, also known as scleroderma, is a rare and complex autoimmune connective-tissue
disease. Once considered an untreatable and unpredictable condition, research advancements
have improved our understanding of its disease pathogenesis and clinical phenotypes
and expanded our treatment armamentarium. Early and accurate diagnosis is essential,
while ongoing efforts to risk stratify patients have a central role in predicting
both organ involvement and disease progression. A holistic approach is required when
choosing the optimal therapeutic strategy, balancing the side-effect profile with
efficacy and tailoring the treatment according to the goals of care of the patient.
A retinal photograph-based deep learning algorithm can detect Alzheimer s disease
with good accuracy, showing its potential for screening Alzheimer s disease in a community
setting.