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Penn Medicine researchers uncover unexpected molecular pattern in Fragile X Syndrome

Researchers have found new disrupted genes and an unexpected molecular pattern dubbed BREACHes related to Fragile X Syndrome (FXS), a genetic disorder estim

New yorkUnited statesLinda zhouJennifer phillips creminsThomas malachowskiRavi boyaPaul biancoLou gehrigKen chandradossYork stem cell foundationRuth perelman school of medicineNational science foundationChan zuckerberg initiativeEpigenetics institute at penn medicineCenters for diseaseNational institutes of health

Surprising Molecular Pattern in Fragile X Syndrome Revealed

Fragile X Syndrome is linked to significant DNA misfolding leading to gene silencing, affecting synaptic and connective tissues.

Ravi boyaKen chandradossJennifer phillips creminsLou gehrigThomas malachowskiEpigenetics institute at penn medicineCenters for diseaseFragilex syndromeDisease controlEpigenetics institutePenn medicineFragilex messenger ribonucleoproteinRepeat expansion anchoring contactingGenetic mutations

Researchers uncover unexpected molecular pattern in fragile X syndrome

Researchers uncover unexpected molecular pattern in fragile X syndrome
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Ravi boyaKen chandradossThomas malachowskiLinda zhouJennifer phillips creminsLou gehrigCenters for diseaseEpigenetics institute at penn medicineUniversity of pennsylvaniaPerelman school of medicineDisease controlPerelman schoolEpigenetics institutePenn medicineFragilex messenger ribonucleoproteinRepeat expansion anchoring contacting