NICE Recommends Astellas’ EVRENZOâ–¼™ (roxadustat) For Adults With Symptomatic Anaemia Associated With Chronic Kidney Disease EVRENZOTM (roxadustat) is the first hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor to be recommended by NICE1Over 75,000 adults in England and Wales living with.