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Overexpression of KIF11 gene may offset Alzheimer s-related cognitive decline in mice and humans

The overexpression of a gene tied to cell division and the structure and function of neurons may prevent and protect against cognitive decline in both mice and humans with Alzheimer’s disease (AD), according to a new study by scientists at the University of Colorado Anschutz Medical Campus.

United statesRush universityEsteban luceroHuntington potterEmily hendersonGlobal down syndrome foundationUniversity of colorado anschutz medical campusNational institutes of healthLinda crnic institute for down syndromeUniversity of colorado school medicineUniversity of colorado alzheimerCognition centerColorado anschutz medicalColorado alzheimerLinda crnic instituteDown syndrome

Kinesin-5 Gene May Protect Against Alzheimer s Disease

The gene Kinesin-5 or KIF11 accomplishes this despite the fact that amyloid beta, the main component of plaques in the brains of those with AD, is present. In

United statesRush universityHuntington potterEstebanm luceroLinda crnic institute for down syndromeUniversity of colorado school medicineUniversity of colorado alzheimerRush university religious orders studyCognition centerColorado alzheimerLinda crnic instituteDown syndromeColorado schoolReligious orders studyAging projectHeidi chial

Gene involved in neuronal structure and function may protect against Alzheimer s

Gene involved in neuronal structure and function may protect against Alzheimer s
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United statesRush universityEsteban luceroHuntington potterUchealth university of colorado hospitalGlobal down syndrome foundationUniversity of colorado anschutz medical campusNational institutes of healthUniversity of coloradoLinda crnic institute for down syndromeUniversity of colorado school medicineUniversity of colorado alzheimerCognition centerColorado anschutz medicalColorado alzheimerLinda crnic institute

Risk Prediction Models Identify Presymptomatic Alzheimer s Disease

Risk models based on noncognitive measures may predict presymptomatic Alzheimer s disease.

Alzheimer associationNational institute onRush memoryAging projectReligious orders studyMental state examNational instituteAlzheimers diseaseLzheimer diseasePeer reviewCognitive impairmentMild cognitive impairmentMini mental status examMse mini mental status exam

Pseudotime Simulates Disease Progression from Case-Control RNA-Seq

Pseudotime Simulates Disease Progression from Case-Control RNA-Seq
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Israel generalUnited statesSan diegoBar harborGregory carterLaura heathSudeshna dasChelsea weidman burkeAlzheimer association international conferenceJackson labHebrew university of jerusalemJackson laboratoryMassachusetts alzheimer disease research centerHelmholtz center institute of bioinformaticsSage bionetworksAssociation international conference