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Personalized deep brain stimulation that targets a specific brain circuit rapidly and effectively relieved treatment-resistant depression, a single case study shows.

United kingdomVladimir litvakKatherine scangosAndrew krystalUniversity college londonWeill instituteUniversity of california san franciscoScience media centreWeill institute for neurosciencesWellcome centre for human neuroimagingCalifornia san franciscoDepression rating scaleHamilton depression rating scaleMedscape medicalReliable biomarkerWellcome centre