covid-19 variant at the same time was infected with one of these common cold coronaviruses, and both viruses have the potential to enter into a single respiratory cell or gastrointestinal cell, and there was some type of recombination even or sharing event, and the result is some type of hybrid. and so the question is does that mean that this is a less serious coronavirus and more resemble a common cold than it will a serious covid-19 infection? i don t think we know that yet. we are getting anecdotal reports from physicians in south africa that they re not seeing a lot of icu patients with this omicron variant, and some cases it s only an incidental finding. i think we have to be over cautious about interpreting anecdotes and we re going to have to wait to see how this pans out. generally speaking, when viruses mutate, do they become
Helicases involved in genomic maintenance are a class of nucleic-acid dependent ATPases that convert the energy of ATP hydrolysis into physical work to execute irreversible steps in DNA replication, repair, and recombination. Prokaryotic helicases provide simple models to understand broadly conserved molecular mechanisms involved in manipulating nucleic acids during genome maintenance. Our understanding of the catalytic properties, mechanisms of regulation, and roles of prokaryotic helicases in DNA metabolism has been assembled through a combination of genetic, biochemical, and structural methods, further refined by single-molecule approaches. Together, these investigations have constructed a framework for understanding the mechanisms that maintain genomic integrity in cells. This review discusses recent single-molecule insights into molecular mechanisms of prokaryotic helicases and translocases.
eventually a covid variant could evade current vaccines. while the analysis isn t peer reviewed, it is still alarming on top of the all the other information. scientists write that it s unlikely the virus will be eradicated, it s almost certain a variant will eventually emerge that a vaccine won t be able to handle. so i want to go to alma abdulazeez in london for more. what can you tell us? so this is a paper that was published friday by the scientific advisory group, the group that guides policy here for the british government. this is not yet peer reviewed. this is theoretical. but what it does lay out is a few scenarios in which the vaccines are able to evade, rather, the virus is able to evade the vaccines. now, these scientists, this paper, says that is very likely to happen. they are particularly concerned about variants mixing with eachers on, recombination between variants, that s what the paper said. that is of particular concern.
virus could evade the vaccine. and the paper says that it is likely that one of those scenarios will take place and there will be a variation of this virus that can ultimately evade the current vaccines we have. now, here is the good news to that, this is something that scientists are already preparing for because if you go to the recommendations, key is to research the possibility of more vaccines in the fit, thuture, t like booster shots which are already beinged a in in-sistered administered in israel. so this may be an annual or seasonal vaccine that we have to take. and the other issue that scientists raised in this paper that is a matter of high concern is what they call the recombination of other variants. so that could create yet another variant and then that variant could potentially be able to evade the vaccine. so in-so tests warning that
africa has no therapies, and we are left to ourselves simply because we really did not do our homework, or also we have not been given the opportunity to contribute. all right, i ll come to that in a moment, but you re tracking covid variants in africa. what are the chances of new mutations in africa? the chances of new mutations in africa are very high. as long as there s transmission occurring anywhere in the world, there is a possibility of recombination that is that possibility of emergence of new variants. and as such, you know, it s very important and very critical that we basically vaccinate everybody across the world to avoid transmission and avoid the emergence of new variants. we ve seen the new variant of the b1317 emerging in south africa, very early on. now, we have the delta variant in many countries in africa. the combination of the b1351