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Credit: © Paolo Annibale, Ali Isbilir, MDC It all sounds similar to a dance event - but are singles or couples dancing here? This was the question Ali Isbilir and Dr. Paolo Annibale at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) were trying to answer. However, their investigation did not involve a ballroom, but the cell membrane. The question behind their investigation: does a particular protein receptor on the surface of cancer and immune cells appear alone or connect in pairs? The receptor is called CXCR4 - the subject of heated debate among experts in recent years due to its mysterious relationship status. Does it appear in singles or pairs on the cell membrane? And what makes the difference? The research team of the Receptor Signaling Lab at the MDC, has now solved the puzzle of its relationship status for the first time. Their findings were recently published in the journal

Martin lohseMax delbrAli isbilirPaolo annibaleProceedings of the national academy sciencesHelmholtz associationReceptor signaling labMolecular medicineNational academyProfessor martin lohseNature protocolsமார்டின் லோசெஏற்பி சமிக்ஞை ஆய்வகம்மூலக்கூறு மருந்துதேசிய கலைக்கழகம்ப்ரொஃபெஸர் மார்டின் லோசெ