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Researchers use information theory to monitor resistance mechanisms to targeted cancer therapy One of the major challenges in modern cancer therapy is the adaptive response of cancer cells to targeted therapies: initially, these therapies are very often effective, then adaptive resistance occurs, allowing the tumor cells to proliferate again. Although this adaptive response is theoretically reversible, such a reversal is hampered by numerous molecular mechanisms that allow the cancer cells to adapt to the treatment. The analysis of these mechanisms is limited by the complexity of cause and effect relationships that are extremely difficult to observe in vivo in tumor samples. In order to overcome this challenge, a team from the University of Geneva (UNIGE) and the University Hospitals of Geneva (HUG), Switzerland, has used information theory for the first time, in order to objectify

Rastine meratEmily hendersonDepartment of pathologyUniversity of genevaUniversity hospitals of genevaUniversity hospitalsOnco dermatology unitஎமிலி ஹென்டர்சன்துறை ஆஃப் நோயியல்பல்கலைக்கழகம் ஆஃப் ஜிநீவபல்கலைக்கழகம் மருத்துவமனைகள் ஆஃப் ஜிநீவபல்கலைக்கழகம் மருத்துவமனைகள்